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NGC Research Results. The National Gerontology Center (NGC)
considers as its main tasks the promoting, information and organizational
support for the research and development in creating technologies of
increasing the duration of active human life. These are based on prophylaxis
of natural aging. The
basic directions for scientific NGC activity is the following: §
Development
of theoretical basis in prophylaxis of aging; §
Working
out the methods of the aging process diagnostics; §
Creating,
approbation and introduction of geroprotectors: means and methods of aging retardation; §
Study
of methods and technologies of prophylaxis of aging and illnesses,
accompanying it; §
Development
of methods and means of biostimulation, biocorrection and increasing the psychic and physical working
ability of a person. MAIN RESULTS OF ACTIVITY The scientists, united under the aegis of NGC
are performing publication of a series of monographs “Problems of
Gerontology” (at present 8 monographs were issued). They published 27 books (
in Russian), in particular: “The Mathematical basis of gerontology”,
“Fundamental mechanisms of geroprophylaxis, “Pathophysiological mechanics of
the Chronic Fatigue Syndrome”, “Systems Mechanisms and Models of Aging”, “Anti-Aging
Medicine: Fundamental Bases”, - and over 300 of scientific papers in leading journals, such as The
Human Biology, The Rejuvenation Research, The
Advances in Gerontology, The
Reports of the Academy of Sciences, The Hygiene and Sanitary, The Longevity
Report, Science, Mutation Research, The Human Physiology, The Cytology, The
Bulletin of Experimental Biology and Medicine and others, relating to the
studies of aging mechanisms and development of methods of aging prophylaxis.
They are editing the yearbook “Aging Prevention”, journal “The Report of
Regenerative Medicine”. Eight
guides for physicians have been worked out and have been affirmed by
the Ministry of Public Health, in particular: ”Diagnostics and Treatment of
the Chronic Fatigue
Syndrome”, “Quantitative Assessment of Aging, Life Span and Biological
Age”; “General Approaches to Aging Prophylaxis”, “Optimization of
Prophylactic, Healing and Geroprotective Rations with the Help of Computer
System “Nutrition for Health and Longevity” and others. The NGC experts have taken part in the
organization and conducting of 12 international and all-Russia conferences,
discussing gerontological problems, in particular, it initiated all-Russia
conferences “Medical and Biological Problems of Normal and Pathological
Aging” (Moscow, 1994), and “Aging and Longevity: Systems and
Multidisciplinary Approaches” (Moscow, 1997), worked in organizing committees
of “The First Russian Conference of Gerontologists and Geriatres”(Samara,1999)
and nine international conferences “Modern Technologies of Rehabilitation
Medicine (Sochi, 1998-2006) and others. The NGC have developed the new methods of
biological age diagnostics, algorithms and programs for evaluation of
expected life duration and prognosis of survival curves, allowing
significantly reducing the period of lengthy and costly experiments on
testing geroprotectors. Original preparations and equipment have been
created, for example, Biosensor, EASes, Vita- stimulus, preparations based on
deuterium and others, having great potentials for use as geroprotectors in
bioactivation and retardation of aging. A perspective approach has been
developed for bioactivation of anti-oxidant systems of organism protection
using electrically activated systems (EAS), allowing correction of oxidation
and recovering potential of the organism’s liquid mediums. A new
immuno-regulation theory of aging has been created, showing possibilities for
recovery of cell growth potential in old organism by immune tropic means. “A
System Theory of Aging” has been created, presenting the basis of integral
technology of aging prophylaxis, worked out by NGC. A family of computer
systems for diagnostics and prophylaxis of aging has been developed. These works have laid the basis for a new System Technology for Radical Increase of Active Human
Lifespan (STRIAHL). The principal novelty of STRIAHL lies in the
orientation on the diagnostics and correction not of particular illnesses,
but on deep processes of wear and exhausting of functional reserves of the
organism in the course of events of normal vital activity, taking place even
in an absolutely healthy body. This technology exceeds the present foreign
approaches to solving this problem:
The organism has been shown to have a special
system for regulation of cell growth presented by sub-populations of
T-lymphocytes. We have put forward a new immune-regulation theory of aging,
connecting aging and self-renovation reduction directly with regulation
changes in T-lymphatic system of immunity. Experimental influence on this
system permitted to restore in several days the growth potential of tissue of
old animals to the level of the young ones. All this shows that regulation
influences could have an important role in development of age-related changes
in a complete organism and influence on this system could be highly effective
for retardation of aging and biologic stimulation of functions of the aging
organism. |